It is thought that the mechanism by which IgA nephropathy develops is through a series of 4 consecutive “hits” that ultimately lead to kidney damage.1 Learn more about the pathogenesis of IgA nephropathy through this animated video narrated by IgANexus faculty Professor Jonathan Barratt.
References: 1. Rajasekaran A, Julian BA, Rizk DV. IgA Nephropathy: An Interesting Autoimmune Kidney Disease. The American Journal of the Medical Sciences. 2021 Feb 1;361(2):176–94.